Four New Cycloartane Saponins from Curculigo orchioides

Abstract

Four new cycloartane-type triterpene glycosides named curculigosaponins G, H, I, and J have been isolated from rhizomes of Curculigo orchioides (Chinese Name: Xiao Mao; Hypoxidaceae). Their structures were elucidated by FAB-MS, ¹H-, ¹³C-NMR, and 2D-NMR analysis and chemical evidence. A pharmacological study showed that curculigosaponin G increased the weight of the thymus in vivo in mice.

Curculigo orchioides - Hypoxidaceae - cycloartane-type saponins - curculigosaponins G, H, I, and J - immunological activity